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Propitocaine Hydrochloride Powder CAS 1786-81-8 - Local Anesthetic from China Suppliers & Factory
Product Introduction
Prilocaine hydrochloride is a local anesthetic of the amino amide type.
Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia, for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).
In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue. Maximum dosage for dental use: 8.0 mg/kg (2.7 mg/lb), with a maximum dose of 500 mg. Eutectic Mixture of Local Anesthetics (EMLA) containing 5% lidocaine and prilocaine in a cream was found to give effective topical analgesia in normal and diseased skin, making it useful for superficial surgery and various other clinical procedures. To be effective, an adequate amount must be applied under occlusion and at the right time before the intervention.
Product Applications
This medication contains 2 amide-type local anesthetics, lidocaine and prilocaine. It is used on normal, unbroken skin or on the outer genital area to prevent pain before certain procedures such as inserting a needle, skin grafts, or skin laser surgery. It works by temporarily numbing the skin and surrounding area. Do not use this product in the ears.
If this product alone cannot completely numb the area being treated, it may be used to numb the area before a lidocaine injection is given to provide enough pain relief for certain procedures (e.g., removal of genital warts).
Usage and Dosage
Infiltration Anesthesia
0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
Nerve Blocking Anesthesia
Use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural Anesthesia
Use 10 to 30 mL of 1.5% ~ 1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.
Note: In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue.
Details
Frequently Asked Questions
Q1: What is Prilocaine Hydrochloride?
Prilocaine hydrochloride is a local anesthetic of the amino amide type, commonly used to provide temporary numbing and pain relief during medical or dental procedures.
Q2: What are the primary applications of this medication?
It is used on normal, unbroken skin or the outer genital area to prevent pain before procedures like needle insertions, skin grafts, or skin laser surgery. It can also be used in combination with lidocaine (such as EMLA cream) for effective topical anesthesia.
Q3: Can Prilocaine be used in the ears?
No, this product should not be used in the ears.
Q4: What is the recommended dosage for different types of anesthesia?
For infiltration anesthesia, a 0.5% to 1% solution is used. For nerve blocking, a 1% to 2% solution is used. For epidural anesthesia, 10 to 30 mL of a 1.5% to 1% solution is recommended, with a maximum dose of 600 mg.
Q5: What are the potential side effects and how are they treated?
A metabolite of prilocaine may cause an unusual side effect called methemoglobinemia in some patients. If this occurs, it can be treated using methylene blue.
Q6: What is the maximum dosage of Prilocaine for dental use?
The maximum dosage for dental use is 8.0 mg/kg (2.7 mg/lb), up to a absolute maximum dose of 500 mg.