Mgl-3196 Resmetirom Powder CAS 920509-32-6

Resmetirom(CAS 920509-32-6), also named MGL-3196, is a liver-targeted selective thyroid hormone receptor beta (THR-β) agonist API powder. It appears as yellow to orange crystalline solid, with high selectivity for THR-β over THR-α to minimize cardiac and bone side effects. This compound activates hepatic THR-β to boost fatty acid oxidation, reduce intrahepatic fat accumulation, relieve liver inflammation and slow fibrosis progression for MASH treatment.

 Our refined synthesis route delivers stable crystal form, low residual solvents and process impurities. Each batch is inspected by HPLC, moisture and heavy metal analysis before release. Full raw material traceability is maintained in production to guarantee consistent batch quality. It serves as key pharmaceutical raw material for oral solid formulation development, preclinical pharmacological assays and clinical trial material supply for global pharmaceutical enterprises and liver disease research institutes.

1. API raw material for oral tablet formulation of metabolic dysfunction-associated steatohepatitis (MASH) with moderate to advanced liver fibrosis.

2. Pharmacological research compound for in vitro and in vivo studies of THR-β mediated hepatic lipid metabolism and anti-fibrotic mechanism.

3. Reference substance for analytical method validation and impurity profiling during MASH drug development.

4. Preclinical formulation research material for oral dosage form screening, dissolution testing and stability evaluation of liver-targeted therapeutics.

■ Every batch undergoes HPLC, moisture, impurity and appearance testing from raw materials to finished packaging.

■ Organic impurities, residual solvents and heavy metals conform to ICH standards.

■ Unique batch IDs track all production, testing and shipping records.

■ Low-temp, light & moisture resistant storage safeguards product stability.

■ Application consulting, spec interpretation and technical guidance available.