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Local Anesthetic Propitocaine Hydrochloride Powder CAS 1786-81-8 - Buy from China Suppliers and Factory
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Local Anesthetic Propitocaine Hydrochloride Powder CAS 1786-81-8 - Buy from China Suppliers and Factory

Product Overview: Propitocaine Hydrochloride

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English Name: Propitocaine Hydrochloride

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CAS No.: 1786-81-8

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Molecular Formula: C13H21ClN2O

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Molecular Weight: 256.77

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EINECS No.: 217-244-0

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Melting Point: 168-170 °C

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Storage Conditions: Store at 2-8 °C

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As a leading supplier and factory in China, we provide high-quality Propitocaine Hydrochloride, a reliable local anesthetic used in various medical applications. With a precise molecular structure and proven efficacy, our product is essential for professionals seeking effective pain management solutions. Trust our established sourcing and manufacturing capabilities to meet your Propitocaine Hydrochloride requirements efficiently.

    Product Introduction

    Prilocaine hydrochloride is a local anesthetic of the amino amide type.
    Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia, for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA). In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue. Maximum dosage for dental use: 8.0 mg/kg (2.7 mg/lb), with a maximum dose of 500 mg. Eutectic Mixture of Local Anesthetics (EMLA) containing 5% lidocaine and prilocaine in a cream was found to give effective topical analgesia in normal and diseased skin, making it useful for superficial surgery and various other clinical procedures. To be effective, an adequate amount must be applied under occlusion and at the right time before the intervention.

    Product Applications

    This medication contains 2 amide-type local anesthetics, lidocaine and prilocaine. It is used on normal, unbroken skin or on the outer genital area to prevent pain before certain procedures such as inserting a needle, skin grafts, or skin laser surgery. It works by temporarily numbing the skin and surrounding area. Do not use this product in the ears.
    If this product alone cannot completely numb the area being treated, it may be used to numb the area before a lidocaine injection is given to provide enough pain relief for certain procedures (e.g., removal of genital warts).

    Usage and Dosage

    • Infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
    • Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
    • Epidural anesthesia: use 10 to 30 mL of 1.5% ~ 1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.
    In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue.

    Details

    Frequently Asked Questions (FAQ)
    What type of local anesthetic is Prilocaine Hydrochloride?

    Prilocaine hydrochloride is a local anesthetic belonging to the amino amide group. It functions by temporarily numbing the skin and surrounding tissues to block pain sensations during various medical and dental procedures.

    What is the recommended maximum dosage for dental applications?

    For dental use, the maximum recommended dosage of Prilocaine is 8.0 mg/kg (2.7 mg/lb), up to an absolute maximum dose of 500 mg.

    How is Prilocaine applied for dermal anesthesia?

    Prilocaine is commonly combined with lidocaine in a 5% cream (known as EMLA) to provide effective topical numbing on normal, unbroken skin or external genital areas. To ensure effectiveness, it must be applied under occlusion at the correct time prior to the procedure.

    What are the dosage guidelines for infiltration and epidural anesthesia?

    Infiltration anesthesia typically uses a 0.5% to 1% solution (lasting 1 to 1.5 hours). Epidural anesthesia requires 10 to 30 mL of a 1% to 1.5% solution (lasting 2.5 to 3.5 hours), with a strict maximum limit of 600 mg.

    What is a notable side effect of Prilocaine and how is it managed?

    A specific metabolite of prilocaine can lead to an uncommon side effect known as methemoglobinemia. If this condition occurs, it can be clinically treated using methylene blue.