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Local Anesthetic Prilocaine Base Powder CAS 721-50-6 from China Suppliers | High-Quality Factory Product
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Local Anesthetic Prilocaine Base Powder CAS 721-50-6 from China Suppliers | High-Quality Factory Product

Physical Characteristics and Specifications of Prilocaine

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English Name: Prilocaine

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CAS Number: 721-50-6

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Molecular Formula: C13H20N2O

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Molecular Weight: 220.31 g/mol

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EINECS Number: 211-957-0

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Melting Point: 37-38 °C

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Boiling Point (bp0.1): 159-162 °C

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Density: Approximately 1.0117 g/cm³

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As a leading China supplier of pharmaceutical ingredients, our Prilocaine is manufactured under stringent quality control measures at our state-of-the-art factory. With its effective properties and reliable specifications, our Prilocaine is suitable for various medical applications. Trust our dedicated team to provide you with premium quality products that meet industry standards.

    Description

    Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia, for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA). In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue. Maximum dosage for dental use: 8.0 mg/kg (2.7 mg/lb), with a maximum dose of 500 mg. Eutectic Mixture of Local Anesthetics (EMLA) containing 5% lidocaine and prilocaine in a cream was found to give effective topical analgesia in normal and diseased skin, making it useful for superficial surgery and various other clinical procedures. To be effective, an adequate amount must be applied under occlusion and at the right time before the intervention.

    Function

    Procaine is a kind of local anesthetics. With low toxicity but quick and safe effects, procaine is suitable for local anesthesia,applied to the eye, ear, nose, teeth and other department operation, used for infiltration anesthesia, anesthesia and closed therapy supervisor. Procaine is also used in the production of procaine penicillin.

    Application

    This medication contains 2 amide-type local anesthetics, lidocaine and prilocaine. It is used on normal, unbroken skin or on the outer genital area to prevent pain before certain procedures such as inserting a needle, skin grafts, or skin laser surgery. It works by temporarily numbing the skin and surrounding area. Do not use this product in the ears.

    Details

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    Frequently Asked Questions (FAQ)

    Q: What is Prilocaine and how is it commonly used?
    Prilocaine is an amino amide-type local anesthetic. In its injectable form (Citanest), it is widely used in dentistry and for intravenous regional anesthesia (IVRA) due to its low cardiac toxicity. It is also combined with lidocaine for dermal anesthesia.
    Q: What is the recommended maximum dosage of Prilocaine in dentistry?
    For dental applications, the maximum recommended dosage of Prilocaine is 8.0 mg/kg (2.7 mg/lb), up to an absolute maximum limit of 500 mg.
    Q: What are the primary applications of Procaine?
    Procaine is a local anesthetic known for its low toxicity and rapid action. It is commonly used for infiltration anesthesia, nerve blocks, and closed therapy in operations involving the eyes, ears, nose, and teeth. It is also utilized in producing procaine penicillin.
    Q: How does the Lidocaine and Prilocaine combination cream work?
    This combination medication contains two amide-type anesthetics that temporarily numb the skin and surrounding tissues. It is applied to normal, unbroken skin or outer genital areas to prevent pain during needle insertions, skin grafts, or laser surgeries.
    Q: Are there any specific safety precautions for using Lidocaine/Prilocaine cream?
    Yes, this product must not be used in the ears. To ensure its effectiveness, a proper amount should be applied under occlusion at the correct time prior to the planned clinical procedure.
    Q: What is a notable side effect of Prilocaine and how is it managed?
    In some individuals, a metabolite of prilocaine can lead to a condition called methemoglobinemia. If this side effect occurs, it is typically treated using methylene blue.