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Lidocaine Hydrochloride Powder CAS 73-78-9 - China Suppliers and Factory for Local Anesthetic Drug
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Lidocaine Hydrochloride Powder CAS 73-78-9 - China Suppliers and Factory for Local Anesthetic Drug

Product Description

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Product: Lidocaine Hydrochloride

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CAS Number: 73-78-9

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Molecular Formula: C14H23ClN2O

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Molecular Weight: 270.8

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Physical Characteristics and Index

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English Name: Lidocaine Hydrochloride

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CAS Number: 73-78-9

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Molecular Formula: C14H23ClN2O

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Molecular Weight: 270.8

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EINECS Number: 200-803-8

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As a leading supplier in China, our factory specializes in the production of high-quality Lidocaine Hydrochloride. This essential local anesthetic is widely used in various medical applications, providing effective pain relief. Our commitment to quality and compliance with industry standards makes us a trusted choice for healthcare professionals seeking reliable pharmaceutical products. Contact us today to learn more about our offerings and how we can meet your needs.

    What is lidocaine?

    Lidocaine acts as a local anesthetic by reversibly blocking sodium channels and blocking the transmission of action potentials along nerve fibers. Sensory fibers are blocked earlier than motor fibers, so low doses of lidocaine can act as a selective sensory block. Lidocaine also has antiarrhythmic effects, belonging to class I and b antiarrhythmic drugs.

    Function

    Lidocaine is suitable for acute ventricular arrhythmias, including premature ventricular beats, ventricular tachycardia, and ventricular fibrillation, caused by acute myocardial infarction, surgery, digitalism, and cardiac catheterization. Secondly, it is also used for epileptic status.

    Application

    Lidocaine is the first-line agent for the treatment of ventricular arrhythmias caused by acute and severe hemodynamic abnormalities. It is also effective for some supraventricular arrhythmias, such as bypass mediated supraventricular tachycardia, and acute episodes or parasympathetic mediated cardioversion of atrial fibrillation. It is widely used for surface anesthesia of mucous membranes (e.g. before endotracheal intubation). EMLA cream is used to anesthetize the skin surface before intravenous catheterization. To ensure the anesthetic effect, apply it to the skin for 45 to 60 minutes, and wrap it with an airtight dressing to promote absorption. EMLA is very useful for ear vein catheterization in rabbits and for intravenous catheterization in young dogs and cats.

    Key Tips & Solubility

    • Solubility: HCl form is soluble in water; base form is insoluble in water (Some Base dissolves in hot water!).
    • Local Anesthesia Strength: The anesthesia effect of some base forms is stronger than HCl.

    Anesthetic Strength Comparison:

    Tetracaine
    >
    Lidocaine
    >
    Benzocaine
    >
    Procaine

    Details

    Frequently Asked Questions (FAQ)
    How does Lidocaine function as a local anesthetic?
    Lidocaine blocks sodium channels reversibly, which halts the transmission of action potentials along nerve fibers. Because sensory fibers are blocked before motor fibers, lower doses can achieve a selective sensory block.
    What cardiac conditions is Lidocaine used to treat?
    It is a first-line treatment for acute ventricular arrhythmias, including premature ventricular beats, ventricular tachycardia, and ventricular fibrillation resulting from myocardial infarction, surgery, digitalism, or cardiac catheterization.
    How should EMLA cream be applied for skin anesthesia?
    EMLA cream should be applied to the skin surface for 45 to 60 minutes and wrapped with an airtight dressing to promote absorption and ensure a proper anesthetic effect before procedures like intravenous catheterization.
    Is Lidocaine applicable in veterinary medicine?
    Yes, EMLA cream is highly useful in veterinary applications, such as ear vein catheterization in rabbits and intravenous catheterization in young dogs and cats.
    What are the solubility differences between Lidocaine HCl and Lidocaine base?
    Lidocaine HCl is soluble in water, whereas Lidocaine base is insoluble in cold water, though some base can dissolve in hot water.
    How does Lidocaine compare to other local anesthetics in strength?
    Based on local anesthesia strength, the hierarchy is: Tetracaine > Lidocaine > Benzocaine > Procaine. Additionally, the anesthetic effect of some base forms is stronger than their HCl counterparts.