Peptides
Leuprorelin Acetate API Powder CAS 74381-53-6
Product Description
Leuprorelin Acetate API, also commonly referred to as Leuprolide Acetate, is a synthetic nonapeptide analog of gonadotropin-releasing hormone (GnRH/LH-RH) and a potent, clinically validated GnRH agonist. With a mature development history and verified pharmacological performance, it serves as a core research-grade and pharmacopoeia-compliant peptide API for global endocrine pharmaceutical R&D.
Compared with native GnRH, Leuprorelin Acetate carries targeted amino acid modifications at position 6 (D-Leu substitution) and position 10 (ethylamide modification), which significantly improve receptor binding affinity and metabolic stability. It exhibits a typical dual-phase pharmacological effect: initial administration stimulates pituitary secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), causing transient elevation of sex hormone levels. Continuous dosing induces GnRH receptor downregulation and desensitization, sustainably suppressing gonadotropin release and sex hormone synthesis, laying a solid foundation for long-term endocrine intervention therapy.
Product Application
1. Reproductive endocrine research: Mechanism studies on GnRH receptor activation, desensitization and hormone feedback regulation
2. Clinical pharmaceutical R&D: Core API intermediate for endocrine therapeutic peptide formulation development
3. Regulatory-grade drug development: Qualified peptide raw material for pharmacopoeia-standard pharmaceutical declaration and production
Quality Assurance
■ GMP-compliant closed production workshops equipped with complete raw material traceability systems.
■ Mature 34-mer long-chain peptide synthesis workflow with precise oxidation impurity control.
■ Independent PTH1R bioassay capability to verify peptide functional potency and bioactivity.
■ Strict batch-to-batch quality control with complete and compliant QC document issuance.
■ Standard cold-chain transportation solutions to stabilize peptide activity during transit.
Our Advantages
We provide DOOR‑TO‑DOOR shipping, including customs clearance.
1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line)
2: Various payment terms accepted (Btc; MoneyGram; WU)
3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging)
4: Efficient delivery (3‑10 DAYS fast delivery service )
5: Best quality (Without any doping, all the products are pure)
6: Good reputation (we have been in this industry for years, earned great trust from our clients from allover the world)
7: Huge Capacity (We have plenty manufacture centers, each day can produce tons of various products.)
8: The most competitive price (manufacture and produce by our own factories)
9. In the end, we have the most professional experienced and dedicated team here.
FAQ
Q1: What is the purity of the Leuprorelin Acetate API Powder you supply?
A: High analytical-grade purity (99%) with a stable assay value, ensuring consistent performance in sensitive chemical reactions.
Q2: What are its core advantages?
A: It is a potent synthetic GnRH agonist nonapeptide with modified amino‑acid sequences for enhanced receptor affinity and metabolic stability. It delivers dual‑phase pharmacological effects for endocrine pharmaceutical R&D.
Q3: Does it meet overseas export standards?
A: Yes. It follows strict GMP production and complies with EP and USP international standards, with complete qualifications to support global export and customs clearance.
Q4: How can I get a sample?
A: Free sample is available, but freight charges will be at your account. The freight cost will be returned or deducted from your future bulk order.
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Contact for Ordering
Whatsapp & Mobile: +86 18765235779
Email:alicehu1988@163.com
Qingdao Little Fox Bio-Tech supplies Flexible procurement options, sample testing, small or bulk orders, global fast transportation, 1-on-1 technical support for research efficiency.