High Purity Propionyl Chloride CAS 79-03-8 Supplier and Factory in China - Liquid for Industrial Use
Description
Propionyl chloride is a colorless to light yellow, volatile, and readily flammable liquid, whose vapors hydrolyze in moist air. It is corrosive, lachrymatory, and has a strongly pungent odor. With water and lower alcohols it reacts vigorously under solvolysis to give the acid or ester. It is used for the introduction of the propionyl group and for the synthesis of propionate esters because of its high reactivity.
Propionyl chloride appears as a colorless liquid with a pungent odor. Corrosive and very irritating to skin and eyes. Used to make other chemicals.
Application
Propionyl chloride is used for the introduction of the propionyl group and for the synthesis of propionate esters because of its high reactivity. It is a chemical intermediate in the preparation of various propionic acid derivatives. It can also be used:
- To convert anisole to 4-methoxypropiophenone and 2-methoxynaphthalene to 1-propio-2-methoxynaphthalene in the presence of Indium(III) chloride (InCl3) impregnated mesoporous Si-MCM-41 catalyst.
- For chlorination in the presence of sulfuryl chloride and peroxides to form α-chloropropionyl chloride and β-chloropropionyl chloride.
- In reaction with (hydroxypropyl)cellulose to form the propanoate ester, [(propionyloxy)propyl]cellulose.
Uses
Propionyl chloride is used as an intermediate in the production of agrochemicals and pharmaceuticals. It serves as an intermediate for dyes, textile auxiliaries and peroxide compounds. It acts as a crop protecting agent.
Reactivity Profile
Acid halides, such as Propionyl chloride, are water reactive; some are violently reactive. They are incompatible with strong oxidizing agents, alcohols, amines, and alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts.
Details
Frequently Asked Questions
Propionyl chloride is a volatile, colorless to light yellow, highly flammable liquid. It features a pungent, corrosive, and lachrymatory nature, making it highly reactive, especially when exposed to moisture or water.
It is primarily used as a chemical intermediate to introduce the propionyl group and synthesize propionate esters. It also plays a vital role in producing agrochemicals, pharmaceuticals, dyes, textile auxiliaries, and crop-protecting agents.
As an acid halide, it reacts vigorously under solvolysis when mixed with water or lower alcohols, yielding the corresponding propionic acid or propionate esters. Its vapors also hydrolyze easily in moist air.
Propionyl chloride is highly corrosive and causes severe irritation to the skin and eyes. It is also lachrymatory (causes tearing) and volatile, requiring strict handling precautions in well-ventilated environments.
It is highly incompatible with water, strong oxidizing agents, alcohols, amines, and alkali. Mixing it with diisopropyl ether or other ethers in the presence of trace metal salts can trigger a violent or explosive reaction.