High Purity Propionyl Chloride CAS 79-03-8 from China Suppliers and Factory - Liquid Chemical Product
Description
Propionyl chloride is a colorless to light yellow, volatile, and readily flammable liquid, whose vapors hydrolyze in moist air. It is corrosive, lachrymatory, and has a strongly pungent odor. With water and lower alcohols it reacts vigorously under solvolysis to give the acid or ester. It is used for the introduction of the propionyl group and for the synthesis of propionate esters because of its high reactivity.
Propionyl chloride appears as a colorless liquid with a pungent odor. Corrosive and very irritating to skin and eyes. Used to make other chemicals.
Application
Propionyl chloride is used for the introduction of the propionyl group and for the synthesis of propionate esters because of its high reactivity. It is an chemical intermediate in the preparation of various propionic acid derivatives, It can also be used:
- To convert anisole to 4-methoxypropiophenone and 2-methoxynaphthalene to 1-propio-2-methoxynaphthalene in the presence of Indium(III) chloride (InCl3) impregnated mesoporous Si-MCM-41 catalyst.
- For chlorination in the presence of sulfuryl chloride and peroxides to form α-chloropropionyl chloride and β-chloropropionyl chloride.
- In reaction with (hydroxypropyl)cellulose to form the propanoate ester, [(propionyloxy)propyl]cellulose.
Uses
Propionyl chloride is used as an intermediate in the production of agrochemicals and pharmaceuticals. It serves as an intermediate for dyes, textile auxiliaries and peroxide compounds. It acts as a crop protecting agent.
Reactivity Profile
Safety Warning & Compatibility
Acid halides, such as Propionyl chloride, are water reactive; some are violently reactive. They are incompatible with strong oxidizing agents, alcohols, amines, and alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts.
Product Details
Frequently Asked Questions
Q
What is Propionyl chloride?
Propionyl chloride is a colorless to light yellow, volatile, and highly flammable liquid with a pungent, corrosive odor. It is widely used as a chemical intermediate to introduce propionyl groups and synthesize propionate esters.
Q
What are the primary applications of Propionyl chloride?
It is mainly used in chemical synthesis to convert anisole to 4-methoxypropiophenone, to synthesize propanoate esters when reacted with (hydroxypropyl)cellulose, and for chlorination processes to yield α-chloropropionyl and β-chloropropionyl chloride.
Q
In which industries is Propionyl chloride utilized?
It serves as an essential intermediate in the manufacturing of agrochemicals, pharmaceuticals, crop protecting agents, dyes, textile auxiliaries, and peroxide compounds.
Q
How does Propionyl chloride react with water and alcohols?
Propionyl chloride reacts vigorously under solvolysis when exposed to water and lower alcohols, resulting in the formation of the corresponding propionic acid or propionate esters.
Q
What are the reactivity hazards of Propionyl chloride?
It is highly water-reactive and incompatible with strong oxidizing agents, alcohols, amines, and alkalies. Additionally, it may react violently or explosively if mixed with ethers (such as diisopropyl ether) in the presence of trace metal salts.





